Poxviruses: Man’s Best Friend. (Or How I Learned to Stop Worrying and Love the Virus)
Poxviruses and humans have had a chequered past. Once the scourge known as smallpox routinely devastated human populations, some estimates are as high as 200 million mortalities last century. However the discovery of a tame version of the virus led to Edward Jenner to demonstrate the practise we now know as vaccination, which has gone some way to repairing the reputation of this virus. My research is built on the premise the these viruses still have much to teach us about many aspects of virology and host cell biology. And one of the most novel and exciting applications may be just around the corner.