Antibiotic

Event Date: 
Wednesday, July 27, 2011 - 19:15 - 20:00
Institution: 
University of Queensland
Title: 

The healthy human gut microbiota and how chemotherapy and antibiotics affect its composition.

Abstract: 

Recent science associates the gut microbiota composition with the development of complex diseases such as for example cardio-vascular diseases, diabetes and inflammatory bowel diseases. Now, the human gastro-intestinal microbiota must be understood as a microbial organ whose metabolism provides essential functions to the host rather than just supplementary nutrient acquisition.
The first aim of this talk is to discuss what makes a “healthy” gut microbiota together with results from analysing vegetarian and elderly gut microbiota.
The second aim will be to discuss results from analysing the gut microbiota of people undergoing chemotherapy and antibiotics.
Whether (and how) diet and age affect the gut microbiota composition is not only really interesting; knowing the diversity of healthy gut microbiotas may help us to decide which composition to restore a perturbed microbiota to, for example after chemotherapy and antibiotic treatment.

Event Date: 
Wednesday, April 27, 2011 - 18:00 - 18:15
Institution: 
Maquarie University
Title: 

Transcriptome led microbial discovery.

Abstract: 

Using a genome wide transcriptomic approach, Karl was able to unravel the role of the Pseudomonas global
activator system (GacA/GacS) in the regulation of an extremely broad range of functions including iron acquisition, oxidative stress response, secondary metabolism and motility. Similar work in Acinetobacter baumannii, a bacterium that is emerging as a major human pathogen due to multiple drug resistance, has revealed the antibiotic efflux to be major mode of resistance and led to the discovery of novel resistance proteins. Karl is a post-
doctoral fellow at Macquarie University working in Prof. Ian Paulsen’s group.

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