Event Date: 
Wednesday, April 30, 2014 - 18:15 - 18:30

Genetic diversity of Group I Clostridium botulinum and Clostridium sporogenes


Whilst classified as a single bacterial species, Clostridium botulinum comprises a phylogenetically and physiologically diverse collection of organisms. Members of this species are linked together based solely on the production of botulinum neurotoxin (BoNT); amongst most lethal natural toxin produced. Isolates that do not produce BoNT are taxonomically considered a separate species, such as Clostridium sporogenes. Given the species delineation is based solely on an unstable phenetic trait presents increasing challenges in a post-genomic era, particularly with increasing evidence pointing towards the lateral acquisition of BoNT production in many strains. Here, the pan-genome of Group I C. botulinum and C. sporogenes is presented, describing the genetic diversity of these species, highlighting the incongruent taxonomy of these organisms and presenting insights into the acquisition of BoNT within this group.

Many scientific minds gathered together for a series of talks on a warm October evening at the Australian Museum.

The first presenter, Martin Ostrowski from Macquarie University continued from last month’s marine microbiology theme by presenting the genetics and ecology of Synechococcus. He demonstrated the distribution patterns of Synechococcus lineages are similar in different ocean systems with comparable environmental conditions. However, specific Synechococcus lineages show a distinct distribution pattern at a global scale. This finding may be useful to predict bacterial community structures in marine ecosystems.
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