Bacteriophages

Event Date: 
Wednesday, March 6, 2013 (All day) - Thursday, March 7, 2013 (All day)

The Molecular Microbiology Meeting for 2013 has been booked for March 6th and 7th at Waterview in Bicentenial Park, Sydney, NSW. Please put the date in your diaries.

Note that the venue has changed and we are planning a meeting over 2 days. For those travelling interstate there is accommodation nearby at the Novotel and Ibis Hotels. You can book accommodation on the registration page.

Holding the meeting over 2 days has allowed us to invite more speakers and make more space for oral presentations selected from abstracts so please plan your abstract and register for the meeting so that we can include you in the program. Closing date for oral presentations will be October 26th.

The program will include:
Professor David Livermore - Drug resistance (Keynote) University of East Anglia (UEA) and Health Protection Agency, London UK

A/Professor Leo Poon - Emerging viruses (Keynote) University of Hong Kong

Professor Tom Riley -    C.difficile (Keynote) University of Western Australia

Event Date: 
Tuesday, April 24, 2012 - 19:15 - 20:00
Institution: 
Nanyang Technological University, Singapore / UNSW
Title: 

The Great Escape: Biofilm formation and dispersal

Abstract: 

Bacteria form biofilms on almost all surfaces, ranging from ship hulls to cooling towers, to indwelling biomedical devices.  Biofilms also play positive roles, for example, floc and granule formation for the biological remediation of contaminated water.  Therefore, there is strong drive to understand the processes of biofilm formation, to either eliminate biofilm formation in some industrial processes and human health, or to encourage their formation, for processes such as remediation.  To develop innovative, environmentally friendly, biofilm control technologies, it is essential to understand the process of biofilm formation and how bacteria control the process of dispersal. 
Bacteria rapidly respond to changes in nutrient conditions, and we have shown that depletion of nutrients, e.g. carbon limitation or nitrogen, can lead to dispersal of bacterial biofilms.  This process is mediated via an intracellular second messenger cascade, using cAMP and c-di-GMP and may also be linked to other physiological signals such as nitric oxide mediated dispersal. 
We have also shown that biofilm development and dispersal is dependent on a prophage carried by Pseudomonas aeruginosa.  The phage plays an important role in multiple aspects of biofilm development and stability and we are beginning to unravel the mechanisms result in phage conversion which ultimately are linked to biofilm development.

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